Comparison of sulphur dioxide and metabisulphite airway reactivity in subjects with asthma.
نویسندگان
چکیده
منابع مشابه
Comparison of sulphur dioxide and metabisulphite airway reactivity in subjects with asthma.
BACKGROUND In asthmatic subjects bronchoconstriction is induced by inhalation of the common food preservatives sulphur dioxide (SO2) and metabisulphite (MBS). SO2 and MBS challenges share many similarities, but it is not known whether they are equivalent. In this study of subjects with mild clinical asthma equivalence was assessed by comparing SO2 and MBS reactivity by estimating the total dose...
متن کاملRefractoriness to inhaled sodium metabisulphite in subjects with mild asthma.
Refractoriness occurs after challenges causing mediator release in asthma, by a mechanism which may involve inhibitory prostaglandins. Bronchoconstriction due to inhaled sodium metabisulphite is thought to involve neural pathways and to be independent of mediator release; whether it shows refractoriness is uncertain. We have sought evidence of refractoriness to the bronchoconstrictor response t...
متن کاملSulphur dioxide sensitivity and plasma antioxidants in adult subjects with asthma.
OBJECTIVES To screen adult subjects with asthma for sensitivity to inhaled sulphur dioxide (SO2) and identify subject characteristics associated with that sensitivity. Medication use, symptoms, and plasma antioxidant nutrients between SO2 responders and non-responders were compared. METHODS Adult subjects (ages 18-39 years) with asthma were exposed to 0.5 ppm SO2 for 10 minutes during moderat...
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ژورنال
عنوان ژورنال: Thorax
سال: 1994
ISSN: 0040-6376
DOI: 10.1136/thx.49.3.250